The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2025

Filed:

Mar. 17, 2023
Applicant:

Wave Life Sciences Ltd., Singapore, SG;

Inventors:

Keith Andrew Bowman, Stow, MA (US);

Chandra Vargeese, Schwenksville, PA (US);

David Charles Donnell Butler, Medford, MA (US);

Pachamuthu Kandasamy, Lexington, MA (US);

Mohammed Rowshon Alam, Hopkinton, MA (US);

Mamoru Shimizu, Arlington, MA (US);

Stephany Michelle Standley, Wakefield, MA (US);

Vincent Aduda, Acton, MA (US);

Gopal Reddy Bommineni, Belmont, MA (US);

Snehlata Tripathi, Waltham, MA (US);

Ilia Korboukh, Needham Heights, MA (US);

Assignee:

WAVE LIFE SCIENCES LTD., Singapore, SG;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07H 21/04 (2013.01);
Abstract

Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.


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