Company Filing History:
Years Active: 2004-2006
Title: The Innovative Contributions of Carol Pearcy Howard
Introduction
Carol Pearcy Howard, an esteemed inventor based in Fenton, MO, has made significant strides in the field of biomedical innovation. With three patents to his name, Howard's inventions focus on critical advancements in understanding and treating diseases through innovative methodologies. His work is particularly relevant in the context of proteolytic enzyme activity and metalloprotease inhibition, showcasing his dedication to improving health outcomes.
Latest Patents
Among Howard's latest patents is a groundbreaking method for identifying and quantifying peptides derived from collagen type II cleavage. This patent introduces a mass spectrometric analysis technique aimed at detecting specific peptide fragments with known mass-to-charge ratios. The identification and quantification of these peptides allow for assessing proteolytic enzyme activity in conditions such as osteoarthritis and rheumatoid arthritis. Additionally, it provides insights into the efficacy of enzyme-blocking agents.
Another notable patent by Howard is focused on an aromatic sulfone hydroxamic acid metalloprotease inhibitor. This invention outlines a treatment process that effectively targets matrix metalloprotease (MMP) enzymes such as MMP-2, MMP-9, and MMP-13, while minimizing the inhibitory effects on MMP-1. The patent details compounds with selective activities and outlines processes for their manufacture, contributing valuable options for treating conditions associated with pathological MMP activity.
Career Highlights
Carol Pearcy Howard is currently associated with Pharmacia Corporation, where he continues to push the boundaries of biomedical research and innovation. His role in the company underscores his commitment to enhancing therapeutic strategies through research and invention. With a strong focus on practical applications of scientific findings, Howard's career has been marked by contributions that are both innovative and impactful.
Collaborations
Throughout his career, Howard has collaborated with notable professionals in the field, including Thomas E. Barta and Daniel Paul Becker. These collaborations have played an essential role in the development and refinement of his patented inventions, fostering a team-oriented approach to tackling complex biomedical challenges.
Conclusion
Carol Pearcy Howard exemplifies the spirit of innovation in the biomedical field. Through his groundbreaking patents and fruitful collaborations, he has committed himself to advancing our understanding and treatment of various diseases. His work not only showcases his inventive prowess but also underscores the importance of continued research and development in improving healthcare solutions.