Newton Highlands, MA, United States of America

Carlo Brugnara


Average Co-Inventor Count = 3.4

ph-index = 9

Forward Citations = 162(Granted Patents)


Location History:

  • Newton Highlands, MA (US) (1993 - 2009)
  • Boston, MA (US) (2017 - 2019)

Company Filing History:


Years Active: 1993-2019

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22 patents (USPTO):Explore Patents

Title: **Carlo Brugnara: Innovator in Malaria Treatment and Sickle Cell Disease Diagnostics**

Introduction

Carlo Brugnara, based in Newton Highlands, MA, is a prolific inventor known for his significant contributions to the fields of malaria treatment and sickle cell disease diagnostics. With a total of 22 patents to his name, Brugnara's innovative approaches have the potential to transform medical therapies and improve patient outcomes.

Latest Patents

Among Brugnara's most recent patents is a groundbreaking method for treating malaria using potassium channel inhibitors. This invention relates specifically to anti-malarial strategies that involve administering potassium channel inhibitors to malaria-affected subjects. These inhibitors are characterized by their wide bioavailability, extended half-life, and favorable toxicity profiles, while exhibiting high potency against malaria-causing parasites. Notably, some embodiments focus on inhibitors of calcium-activated potassium channels, such as the Gardos channel.

Additionally, Brugnara has developed multiphase systems for diagnosing sickle cell disease. This invention includes an aqueous multi-phase system featuring two or more phase-separated components. Each aqueous phase possesses distinct densities, facilitating effective diagnosis through the interaction of phase components that include specific polymers.

Career Highlights

Carlo Brugnara has made notable contributions during his tenure at prestigious institutions, including the President and Fellows of Harvard College and the Children's Medical Center Corporation. His combined expertise in both research and practical applications has played a critical role in advancing medical diagnostics and therapeutics.

Collaborations

Throughout his career, Brugnara has collaborated with prominent figures in the field, including Jose Alberto Halperin and Richard John Lombardy. These collaborations have enriched his research, fostering innovative solutions to complex medical challenges.

Conclusion

Carlo Brugnara stands out as an inventor whose work addresses significant health issues such as malaria and sickle cell disease. His innovative patents and collaborations underscore his commitment to advancing medical science and improving patient care. As research evolves, Brugnara's contributions will undoubtedly continue to shape the future of medical innovations.

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