The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Apr. 28, 2014
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

George M. Whitesides, Newton, MA (US);

Ashok A. Kumar, Medford, MA (US);

Jonathan W. Hennek, Somerville, MA (US);

Caeul Lim, Boston, MA (US);

Yovany Moreno, Cambridge, MA (US);

Charles R. Mace, Auburn, NY (US);

Manoj T. Duraisingh, Cambridge, MA (US);

Matthew R. Patton, Cambridge, MA (US);

Si-yi Ryan Lee, Cambridge, MA (US);

Gaetana D'Alesio-Spina, Cambridge, MA (US);

Carlo Brugnara, Boston, MA (US);

Thomas P. Stossel, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/49 (2006.01); G01N 33/80 (2006.01); G01N 15/05 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/80 (2013.01); G01N 15/05 (2013.01); G01N 33/491 (2013.01); G01N 2015/003 (2013.01); G01N 2015/0073 (2013.01); G01N 2015/0076 (2013.01); G01N 2800/22 (2013.01);
Abstract

An aqueous multi-phase system for diagnosis of sickle cell disease is described, including two or more phase-separated phases including: a first aqueous phase including a first phase component and having a first density between about 1.025 g/cmand about 1.095 g/cm; and a second aqueous phase including a second phase component and having a second density between about 1.100 g/cmand about 1.140 g/cm; wherein the first density is lower than the second density; and each of the first and second phase components include at least one polymer.


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