Company Filing History:
Years Active: 1999-2006
Title: Bruce L Frank: Innovator in Oligonucleotide Technology
Introduction
Bruce L Frank is a notable inventor based in Marlborough, MA (US), recognized for his contributions to the field of oligonucleotide technology. With a total of four patents to his name, Frank has made significant advancements in the treatment of viral infections, particularly those caused by hepatitis B and human papillomavirus (HPV).
Latest Patents
Frank's latest patents include innovative synthetic oligonucleotides that are specifically designed to target the hepatitis B virus (HBV). The invention discloses synthetic oligonucleotides that are complementary to both contiguous and noncontiguous regions of the HBV RNA. Additionally, it outlines methods and kits aimed at inhibiting the replication and expression of HBV, as well as treating HBV infections and associated conditions. Another significant patent focuses on HPV-specific oligonucleotides. This invention reveals synthetic oligonucleotides that are complementary to a nucleic acid spanning the translational start site of the human papillomavirus gene E1, including at least 15 nucleotides. It also provides methods and kits for inhibiting the replication of HPV, detecting HPV, and treating HPV infections.
Career Highlights
Bruce L Frank has established a successful career at Hybridon, Inc., where he has been instrumental in developing cutting-edge technologies in the field of molecular biology. His work has not only advanced scientific understanding but has also paved the way for new therapeutic approaches to combat viral infections.
Collaborations
Throughout his career, Frank has collaborated with esteemed colleagues, including Peter C Roberts and John S Mills. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
In summary, Bruce L Frank is a distinguished inventor whose work in oligonucleotide technology has made a significant impact on the treatment of viral infections. His innovative patents and contributions to Hybridon, Inc. highlight his dedication to advancing medical science.
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