The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2006

Filed:

Jul. 28, 1997
Applicants:

Bruce L. Frank, Marlborough, MA (US);

Peter C. Roberts, Holliston, MA (US);

John Goodchild, Westborough, MA (US);

J. Charles Craig, Welwyn Garden, GB;

John S. Mills, Welwyn Garden, GB;

Andrew Slade, Welwyn Garden, GB;

Robert E. Kilkuskie, Shrewsbury, MA (US);

Noel A. Roberts, Harpenden, GB;

Raymond Jupp, Welwyn Garden, GB;

Inventors:

Bruce L. Frank, Marlborough, MA (US);

Peter C. Roberts, Holliston, MA (US);

John Goodchild, Westborough, MA (US);

J. Charles Craig, Welwyn Garden, GB;

John S. Mills, Welwyn Garden, GB;

Andrew Slade, Welwyn Garden, GB;

Robert E. Kilkuskie, Shrewsbury, MA (US);

Noel A. Roberts, Harpenden, GB;

Raymond Jupp, Welwyn Garden, GB;

Assignee:

Hybridon, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses synthetic oligonucleotides complementary to contiguous and noncontiguous regions of the HBV RNA. Also disclosed are methods and kits for inhibiting the replication and expression of HBV, and for treating HBV infections and associated conditions.


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