The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2002

Filed:

Jul. 02, 1997
Applicant:
Inventors:

Peter C. Roberts, Holliston, MA (US);

Bruce L. Frank, Marlborough, MA (US);

David E. Szymkowski, Mountain View, CA (US);

John S. Mills, Farnham Common, GB;

John Goodchild, Westborough, MA (US);

Jia L. Wolfe, Somerville, MA (US);

Robert E. Kilkuskie, Shrewsbury, MA (US);

Isobel M. Greenfield, St. Albans, GB;

Veronica Sullivan, St. Albans, GB;

Assignee:

Hybridon, Inc., Milford, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; C12Q 1/68 ;
U.S. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; C12Q 1/68 ;
Abstract

The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.


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