Company Filing History:
8 out of 349 
2 out of 168 
2 out of 402 
Years Active: 1996-2021
Title: The Innovations of Bruce Edward Blough
Introduction
Bruce Edward Blough is a notable inventor based in Raleigh, NC, with a significant contribution to the field of pharmacology. He holds a total of eight patents, showcasing his innovative approach to developing compounds that address various medical conditions. His work primarily focuses on neurotransmitter systems and their implications for treating mental health disorders.
Latest Patents
Among his latest patents, Blough has developed monoamine reuptake inhibitors. This invention provides bupropion analogue compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity. Another significant patent involves vinylogous phenethylamines as neurotransmitter releasers. This disclosure provides monoamine neurotransmitter releaser and/or monoamine uptake inhibitor compounds that have biogenic amine transporter activity but lack substantial activity at 5-HT receptor subtypes. The phenethylamine or vinylogous phenethylamine compounds are useful in treating diseases, conditions, and/or disorders mediated by the activity of one or more of the monoamine neurotransmitters.
Career Highlights
Blough has had a distinguished career, working with reputable organizations such as the Research Triangle Institute and Dignity Health. His experience in these institutions has allowed him to collaborate with other experts in the field and contribute to groundbreaking research.
Collaborations
Some of his notable coworkers include Richard B. Rothman and Frank Ivy Carroll. Their collaborative efforts have further advanced the understanding of neurotransmitter systems and their therapeutic potential.
Conclusion
Bruce Edward Blough's contributions to the field of pharmacology through his innovative patents highlight his commitment to improving mental health treatment. His work continues to influence the development of new therapeutic options for various conditions.