The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
May. 20, 2011
Bruce E. Blough, Raleigh, NC (US);
Richard Rothman, Ellicott City, MD (US);
Antonio Landavazo, Raleigh, NC (US);
Kevin M. Page, Willow Spring, NC (US);
Ann Marie Decker, Durham, NC (US);
Bruce E. Blough, Raleigh, NC (US);
Richard Rothman, Ellicott City, MD (US);
Antonio Landavazo, Raleigh, NC (US);
Kevin M. Page, Willow Spring, NC (US);
Ann Marie Decker, Durham, NC (US);
Research Triangle Institute, Research Triangle Park, NC (US);
The United States of America, As Represented by the Secretary Department of Health and Human Services, Washington, DC (US);
Abstract
Provided herein are compounds and prodrugs and methods of preparation of compounds and prodrugs that are capable of functioning as releasers and/or uptake inhibitors of one or more monoamine neurotransmitters, including dopamine, serotonin, and norepinephrine. Also provided are pharmaceutical compositions comprising one or more of these compounds or prodrugs, which may further comprise one or more additional therapeutic agents. Also provided are methods of treatment of various conditions that may be responsive to modification of monoamine neurotransmitter levels, such as pre-obesity, obesity, addiction, and depression.