Brian Joseph Hofilena

This inventor holds 15 USPTO granted patents and 8 published patent applications and 3 EPO patents. Top assignees: Samumed, LLC, Biosplice Therapeutics, Inc., Tenarx, Inc.. Active years: 2017-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Brian Joseph Hofilena. Retrieved from https://idiyas.com/inventor/brian-joseph-hofilena

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 15 (Patent Applications = 8)

% Patents Active = 100.0

EPO Patents = 3 (Patent Applications = 8)

Average Co-Inventor Count = 7.1

ph-index = 3

Forward Citations = 73(Granted Patents)

Company Filing History:

Biosplice Therapeutics, Inc.

Years Active: 2017-2026

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15 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12729205 - 4-alkoxypyrrolo[2,1-f][1,2,4]triazines and preparation and uses thereof (2026-09-08),

2. 12134625 - Pyrrolo[2,1-f][1,2,4]triazines and preparation and uses thereof (2024-11-05),

3. 11713320 - 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof (2023-08-01),

4. 11673881 - Isoquinolin-3-yl carboxamides and preparation and use thereof (2023-06-13),

5. 11174244 - Isoquinolin-3-yl carboxamides and preparation and use thereof (2021-11-16),

6. 10934297 - 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof (2021-03-02),

7. 10759799 - Indazole containing macrocycles and therapeutic uses thereof (2020-09-01),

8. 10703748 - Diazanaphthalen-3-yl carboxamides and preparation and use thereof (2020-07-07),

9. 10669240 - 5-substituted indazole-3-carboxamides and preparation and use thereof (2020-06-02),

10. 10653688 - 6-(6-membered heteroaryl and aryl)isoquinolin-3-yl carboxamides and preparation and use thereof (2020-05-19),

11. 10604514 - 6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof (2020-03-31),

12. 10556885 - Isoquinolin-3-YL carboxamides and preparation and use thereof (2020-02-11),

13. 10508099 - Isoquinolin-3-yl carboxamides and preparation and use thereof (2019-12-17),

14. 10287267 - Isoquinolin-3-yl carboxamides and preparation and use thereof (2019-05-14),

15. 9745271 - 5-substituted indazole-3-carboxamides and preparation and use thereof (2017-08-29),

Title: Innovator Spotlight: Brian Joseph Hofilena

Introduction:

Brian Joseph Hofilena, a prolific inventor based in San Diego, CA, has made significant contributions to the field of pharmaceuticals with his groundbreaking patents and innovative research.

Latest Patents:

Hofilena's latest patents include the development of 5-heteroaryl substituted indazole-3-carboxamides and isoquinolin-3-yl carboxamides. These compounds have shown potential in treating a wide range of diseases and pathologies related to Wnt pathway signaling, including various forms of cancer, Alzheimer's disease, and autoimmune conditions.

Career Highlights:

With an impressive portfolio of 13 patents to his name, Hofilena has demonstrated a keen ability to translate scientific discoveries into tangible solutions for pressing healthcare challenges. He has worked with esteemed companies such as Samumed and Biosplice Therapeutics, driving cutting-edge research and development in the pharmaceutical industry.

Collaborations:

Throughout his career, Hofilena has collaborated closely with top-tier professionals in the field, including notable coworkers like Gopi Kumar Mittapalli and Sunil Kumar KC. These collaborations have enhanced the scope and impact of his innovative work, fostering a culture of collaboration and exchange of ideas.

Conclusion:

In conclusion, Brian Joseph Hofilena stands out as a visionary inventor who continues to push the boundaries of pharmaceutical research. His patents represent a significant step forward in the development of targeted therapies for a range of complex diseases, underscoring his commitment to innovation and excellence in the field.

Profile summary based on public USPTO records.