The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Oct. 06, 2021
Biosplice Therapeutics, Inc., San Diego, CA (US);
Sunil Kumar KC, San Diego, CA (US);
Gopi Kumar Mittapalli, San Diego, CA (US);
Brian Joseph Hofilena, San Diego, CA (US);
Joseph Timothy Marakovits, Encinitas, CA (US);
Chandramouli Chiruta, San Diego, CA (US);
Chi Ching Mak, San Diego, CA (US);
Jianguo Cao, San Diego, CA (US);
BioSplice Therapeutics, Inc., San Diego, CA (US);
Abstract
Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.