Company Filing History:
4 out of 379 
2 out of 7 Years Active: 2012-2016
Title: Brian F Clem: A Pioneer in Anti-Cancer Therapeutics
Introduction
Brian F Clem, based in Louisville, KY, is a notable inventor with a total of four patents to his name. His innovative contributions primarily focus on developing small molecule inhibitors that target key enzymes involved in cancer metabolism, demonstrating his commitment to advancing medical science and therapeutic options for cancer patients.
Latest Patents
Clem's latest patents include significant research on small molecule inhibitors of PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). These inhibitors show potential as anti-cancer therapeutics and involve methods for treating cancer by targeting glycolytic flux. His work provides pharmaceutical compositions containing these compounds and methods for treating tumors effectively.
Additionally, he has developed small molecule choline kinase inhibitors along with screening assays to identify and evaluate these inhibitors’ efficacy in treating neoplastic disorders. These solutions aim to offer safe and effective methods for managing diseases characterized by neoplastic cell proliferation.
Career Highlights
Brian has contributed his expertise to esteemed organizations, notably the University of Louisville Research Foundation, Inc., and Advanced Cancer Therapeutics, LLC. His role in these institutions showcases his dedication to research and the development of groundbreaking therapeutic strategies.
Collaborations
Throughout his career, Clem has collaborated with distinguished colleagues, including Jason Chesney and John Olaf Trent. Their collective efforts amplify the impact of their research, promoting advancements in cancer treatment methodologies.
Conclusion
In summary, Brian F Clem stands out as an influential figure in the field of cancer therapeutics. His patent portfolio highlights his innovative approaches to tackling complex challenges in cancer treatment, solidifying his reputation as a key inventor in medical research. Through his work, he continues to pave the way for future discoveries that have the potential to save lives.