Brian D Frenzel

This inventor holds 16 USPTO granted patents and 3 published patent applications, plus 2 CIPO patents and 2 EPO patents, primarily in Pharmaceutical Innovations. Top assignee: Tosk, Incorporated. Active years: 2011-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Brian D Frenzel. Retrieved from https://idiyas.com/inventor/brian-d-frenzel

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank

USPTO Granted Patents = 16 (Patent Applications = 3)

% Patents Active = 100.0

CIPO Patents = 2 (Patent Applications = 3)

EPO Patents = 2 (Patent Applications = 7)

Average Co-Inventor Count = 3.1

ph-index = 5

Forward Citations = 37(Granted Patents)

Location History:

Los Altos, CA (US) (2011 - 2020)
Mountain View, CA (US) (2022 - 2024)

Company Filing History:

16 out of 22

Tosk, Incorporated

patents

Years Active: 2011-2026

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Areas of Expertise:

Uridine Phosphorylase Inhibitors

RAS GTPase Modulators

Radiation Induced Toxicity

Mucositis Treatment

Methotrexate Adjuvants

Doxorubicin Adjuvants

Pulmonary Disease

Drug Side-Effects

16 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12667571 - Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions (2026-06-30),

2. 12528796 - Modulators of RAS GTPase (2026-01-20),

3. 12508265 - Methods and compositions for reducing radiation induced toxicity (2025-12-30),

4. 12486255 - Modulators of RAS GTPase (2025-12-02),

5. 12419893 - Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine (2025-09-23),

6. 12194043 - Uridine phosphorylase inhibitors to treat or prevent pulmonary disease (2025-01-14),

7. 12109222 - Methods and compositions for treating mucositis (2024-10-08),

8. 11945803 - Modulators of RAS GTPase (2024-04-02),

9. 11446303 - Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions (2022-09-20),

10. RE48253 - Methotrexate adjuvants to reduce toxicity and methods for using the same (2020-10-12),

11. 9468613 - Doxorubicin adjuvants to reduce toxicity and methods for using the same (2016-10-18),

12. 9382287 - Methotrexate adjuvants to reduce toxicity and methods for using the same (2016-07-05),

13. 9061038 - Doxorubicin adjuvants to reduce toxicity and methods for using the same (2015-06-23),

14. 8853227 - Methotrexate adjuvants to reduce toxicity and methods for using the same (2014-10-07),

15. 8227517 - Doxorubicin adjuvants to reduce toxicity and methods for using the same (2012-07-24),

Title: Brian D. Frenzel: Innovator in Therapeutic Methods

Introduction

Brian D. Frenzel is a notable inventor based in Los Altos, California. He has made significant contributions to the field of therapeutics, particularly in the prevention and treatment of various maladies. With a total of 16 patents to his name, his work focuses on innovative methods and compositions that enhance drug effectiveness and reduce side effects.

Latest Patents

Among his latest patents, one notable invention is titled "Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine." This patent outlines methods for improving the therapeutic effectiveness of uridine, which is administered to prevent or reduce adverse events from drugs. The methods include administering an effective amount of a uridine maximizing adjuvant, such as a 2,2'-anhydropyrimidine or its derivatives. Additionally, he has developed compositions for various applications, including the treatment of different disease conditions.

Another significant patent is "Uridine phosphorylase inhibitors to treat or prevent pulmonary disease." This invention relates to compositions and methods for treating pulmonary disorders characterized by fibrosis, such as idiopathic pulmonary fibrosis (IPF) and acute respiratory distress syndrome (ARDS). The administration of a UPase inhibitor, with or without supplemental uridine or its prodrugs, is central to this innovative approach.

Career Highlights

Brian D. Frenzel has worked with prominent organizations, including Tosk, Incorporated and the University of California. His career reflects a commitment to advancing therapeutic methods that address critical health challenges.

Collaborations

Throughout his career, Brian has collaborated with esteemed colleagues, including William A. Garland and Philip Liaw. These partnerships have contributed to the development of his innovative patents and research.

Conclusion

Brian D. Frenzel stands out as an influential inventor in the field of therapeutics. His innovative patents and collaborations highlight his dedication to improving health outcomes through advanced methodologies. His work continues to pave the way for future advancements in medical treatments.

Profile summary based on public USPTO records.