The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Aug. 06, 2019
Tosk, Inc., Mountain View, CA (US);
Annie L. Lennek, Mountain View, CA (US);
Stephen D. Yanofsky, Mountain View, CA (US);
Brian D. Frenzel, Mountain View, CA (US);
Solomon B. Ungashe, Mountain View, CA (US);
William A. Garland, Mountain View, CA (US);
Philip Liaw, Mountain View, CA (US);
Tosk, Inc., Mountain View, CA (US);
Abstract
RAS modulating compounds and methods of using the same are provided. The compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject compounds can inhibit the growth of cancer cells whose progression is driven by kRAS or a mutated kRAS. Methods of treating a subject for a RAS driven disease including administering a therapeutically effective amount of the subject compound are provided. Also provided are pharmaceutical compositions and kits which include the subject compounds.