Company Filing History:
Years Active: 1994-2002
Title: Brian A Donahue: Innovator in DNA Structure-Specific Recognition
Introduction
Brian A Donahue is a distinguished inventor based in Menlo Park, California, known for his significant contributions to the field of molecular biology and pharmacology. With four patents to his name, he has become an influential figure in developing innovative methods for understanding and addressing genomic lesions caused by chemotherapeutic agents.
Latest Patents
Donahue's latest patents focus on the applications of DNA Structure Specific Recognition Proteins (SSRPs). The methods disclosed in these patents capitalize on SSRPs' ability to bind to genomic lesions formed by chemotherapeutic agents, particularly cisplatin-type drugs. These patents provide groundbreaking techniques that can predict the cytotoxic effects of DNA-damaging agents and the susceptibility of specific eukaryotic cells to genotoxic drugs. Additionally, a method for screening new genotoxic drugs that produce SSRP-recognized lesions in DNA is outlined. Notably, Donahue’s research also includes methods for sensitizing certain eukaryotic cells to the effects of chemotherapeutic agents, thereby enhancing treatment efficacy.
Career Highlights
As a prominent member of the Massachusetts Institute of Technology (MIT), Donahue has made significant strides in cancer research and pharmacogenomics. His innovative approach and research have led to the development of technologies that could fundamentally alter the landscape of cancer therapy.
Collaborations
Throughout his career, Donahue has collaborated with esteemed colleagues like Jeffrey H Toney and John M Essigmann. These partnerships have fostered a collaborative environment that enhances the impact of his research and inventive endeavors.
Conclusion
Brian A Donahue exemplifies the spirit of innovation in modern science. His work not only contributes to understanding DNA damage and repair mechanisms but also holds promise for improving therapeutic options for cancer treatment. As research continues to evolve, Donahue's inventions will likely play a crucial role in shaping future methodologies in molecular medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.