The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 1997
Filed:
Jun. 09, 1994
Brian A Donahue, Menlo Park, CA (US);
Jeffrey H Toney, Westfield, NJ (US);
John M Essigmann, Brookline, MA (US);
Stephen J Lippard, Cambridge, MA (US);
Pieter M Pil, Cambridge, MA (US);
Suzanne L Bruhn, Cambridge, MA (US);
Steven J Brown, Cambridge, MA (US);
Patti J Kellett, Cincinnati, OH (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
DNA structure specific recognition protein of eukaryotic origin and DNA encoding such a factor, as well as probes specific for DNA structure specific recognition protein or DNA encoding it and methods of detecting DNA structure specific recognition protein in eukaryotic cells. In particular, a mammalian cellular factor that selectively recognizes and binds DNA damaged or modified by a drug (the anticancer drug, cis-diamminedichloroplatinum (II) or cisplatin) has been identified.