Inventors with similar research interests:
Location History:
- Ann Arbor, MI (US) (1995 - 2001)
- La Jolla, CA (US) (1997 - 2019)
- San Diego, CA (US) (2012 - 2021)
Company Filing History:
Years Active: 1995-2021
Title: Innovations and Contributions of Bernhard O. Palsson
Introduction
Bernhard O. Palsson is a prominent figure in the field of biotechnology, known for his innovative contributions to the engineering of mammalian cells. Residing in La Jolla, California, he has amassed an impressive portfolio of 50 patents throughout his career. His work primarily focuses on advancements in recombinant protein production, which has profound implications for medical and industrial applications.
Latest Patents
Among his latest patents is a significant innovation concerning engineered mammalian cells that enhance the production of recombinant proteins. This invention pertains to CHO (Chinese Hamster Ovary) cells and other host cells where the expression of various endogenous secreted proteins has been disrupted. This modification aims to provide improved expression levels of proteins of interest. Another noteworthy patent involves mutant cells containing specific mutations in genes such as rpoB, hns/tdk, and others, which leads to increased growth rates, glucose uptake, acetate production, and biomass yield compared to wild-type controls. These advancements indicate the potential for more efficient production processes in biotechnology.
Career Highlights
Bernhard O. Palsson has held vital roles at prestigious institutions, such as the University of Michigan and the University of California. Through his educational endeavors and research initiatives, he has significantly influenced the field of metabolic engineering and synthetic biology, paving the way for groundbreaking innovations.
Collaborations
Throughout his career, Palsson has collaborated with several esteemed professionals, including Stephen G. Emerson and Michael F. Clarke. These partnerships have fostered an environment for innovative research and development, leading to successful outcomes and advancements in their respective fields.
Conclusion
Bernhard O. Palsson's significant contributions to the biotechnology sector through his numerous patents and collaborations have established him as a leading innovator. His work in enhancing mammalian cell engineering for recombinant protein production is a testament to his impact in the industry. As the field continues to evolve, Palsson's research will likely continue to inspire future innovations and advancements.
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