Brookline, MA, United States of America

Benjamin L Ebert

USPTO Granted Patents = 16 

Average Co-Inventor Count = 3.6

ph-index = 2

Forward Citations = 8(Granted Patents)


Location History:

  • Brookline, MA (US) (2013 - 2023)
  • Boston, MA (US) (2018 - 2024)

Company Filing History:


Years Active: 2013-2025

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16 patents (USPTO):Explore Patents

Title: Innovations by Inventor Benjamin Ebert in Cancer Treatment

Introduction

Benjamin Ebert is a notable inventor based in Boston, MA, recognized for his contributions to the field of cancer research and treatment. With a total of two patents to his name, Ebert stands out for his innovative approaches to overcoming challenges associated with chemotherapy-resistant cancers.

Latest Patents

Ebert's latest inventions include groundbreaking methods and compositions for treating chemotherapy-resistant cancer. His first patent outlines methods for increasing sensitivity to chemotherapy, reversing resistance, and identifying resistance or sensitivity in patients. A key feature of this invention is the inhibition of the Protein phosphatase 1D (PPM1D) polypeptide, which could substantially improve treatment outcomes for patients facing tough battles against cancer.

The second patent introduces a molecular switch-mediated control mechanism for engineered cells. This invention allows for the precise induction of activity or degradation of switch-presenting polypeptides through the administration of FDA-approved drugs. Ebert's work here demonstrates a drug-inducible heterodimeric system that leverages the binding of CRBN polypeptides to trigger therapeutic responses. The inclusion of chimeric antigen receptors capable of triggering proteasomal degradation adds a further layer of ingenuity to his work.

Career Highlights

Throughout his career, Benjamin Ebert has made significant strides in the medical research field. He has collaborated with prestigious institutions such as Brigham and Women’s Hospital, Inc., and the General Hospital Corporation. His work has not only advanced scientific understanding but has also aimed to empower clinical applications that benefit patient care.

Collaborations

Ebert has had the privilege of working alongside talented professionals such as Max Jan, contributing to a collaborative environment that fosters innovation and discovery in biotechnology and cancer therapy.

Conclusion

Benjamin Ebert’s contributions to the medical field, particularly in the realm of cancer treatment, highlight his role as a forward-thinking inventor. His patents illustrate a commitment to developing innovative solutions to significant health challenges, potentially offering new hope for patients battling chemotherapy-resistant conditions.

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