The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Dec. 04, 2018
Applicants:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Rob Sellar, Newton, MA (US);
Benjamin Ebert, Brookline, MA (US);
Ofir Wolach, Boston, MA (US);
Kimberly Martinod, Boston, MA (US);
Denisa Wagner, Dover, MA (US);
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Children's Medical Center Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); A61K 31/506 (2006.01); A61P 9/10 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/48 (2006.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61P 9/10 (2018.01); C12Q 1/485 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The methods described herein include methods for the treatment of subjects who have Clonal Hematopoiesis of Indeterminate Potential (CHIP) or a Philadelphia-negative myeloproliferative neoplasm (MPN), e.g., polycythaemia vera (PV) or essential thrombocythaemia (ET), using inhibitors of JAK-STAT signaling.