Location History:
- Bejing, CN (2015)
- Beijing, CN (2007 - 2020)
Company Filing History:
4 out of 13 
1 out of 1 
1 out of 114 Years Active: 2007-2020
Title: Beifen Shen: Innovator in Pharmaceutical Sciences
Introduction
Beifen Shen is a prominent inventor based in Beijing, China, known for his significant contributions to the field of pharmaceutical sciences. With a total of seven patents to his name, he has made remarkable advancements in the treatment of various diseases, particularly those related to inflammation and immunology.
Latest Patents
One of Beifen Shen's latest patents is focused on anti-C5a binding moieties with high blocking activity. This invention relates to binding moieties that specifically target a conformational epitope of C5a, particularly human C5a. The preferred binding moieties are anti-C5a antibodies that can effectively bind to this epitope. These binding moieties are valuable as active agents in pharmaceutical compositions aimed at treating and preventing various acute and chronic diseases, especially acute inflammatory diseases such as systemic inflammatory response syndrome (SIRS) and different degrees of sepsis, including sepsis, severe sepsis, and septic shock.
Another notable patent is the human Tim-3 fusion protein capable of blocking the Tim-3 signaling pathway. This invention provides a human Tim-3-Ig fusion protein that can inhibit the Tim-3 signal pathway. The Ig fusion protein comprises the Tim-3 protein, a human Ig fragment, and a linking sequence. The human Tim-3-Ig gene is synthesized artificially, and an expression vector containing this gene is constructed. The prepared Ig fusion protein undergoes various tests, including expression verification, binding activity, blocking activity in different cell lines, and in vivo experiments in mice. This fusion protein has potential applications in treating immunological diseases caused by high expression of Tim-3.
Career Highlights
Throughout his career, Beifen Shen has worked with notable organizations, including Inflarx GmbH and the Institute of Pharmacology and Toxicology at the Academy of Military Medical Sciences in China. His work in these institutions has contributed to the advancement of pharmaceutical research and development.
Collaborations
Beifen Shen has collaborated with esteemed colleagues, including Renfeng Guo and Yan Li, further enhancing the impact of his research and innovations in the field.
Conclusion
Beifen Shen's contributions to pharmaceutical sciences through his innovative patents and collaborations highlight his role as a leading inventor in the industry. His work continues to pave the way for advancements in the treatment of critical health conditions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.