Company Filing History:
Years Active: 1992-1995
Title: B John Bergot: Innovator in Nucleic Acid Sequencing
Introduction
B John Bergot is a notable inventor based in Redwood City, CA (US). He has made significant contributions to the field of nucleic acid sequencing, holding a total of 5 patents. His work has advanced the methodologies used in genetic research and diagnostics.
Latest Patents
Among his latest patents is the invention related to the chromatographic separation of phosphorothioate oligonucleotides. Additionally, he has developed a spectrally resolvable set of rhodamine dyes for use in the chain termination method of nucleic acid sequencing. This innovative approach involves attaching different rhodamine dyes, such as tetramethylrhodamine, rhodamine X, rhodamine 6G, and rhodamine 110, to the base of each dideoxynucleotide. These labeled dideoxynucleotides are incorporated into growing DNA chains by Taq DNA polymerase, enhancing the efficiency and accuracy of sequencing.
Career Highlights
B John Bergot has worked with prominent companies in the biotechnology sector, including Applied Biosystems, LLC and Lynx Therapeutics, Inc. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking advancements in the field.
Collaborations
Throughout his career, Bergot has collaborated with esteemed colleagues such as Wojciech J Stec and Bogdan Uznanski. These partnerships have fostered innovation and have been instrumental in the development of his patented technologies.
Conclusion
B John Bergot's contributions to nucleic acid sequencing exemplify the impact of innovative thinking in biotechnology. His patents and collaborations continue to influence the field, paving the way for future advancements.