The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 1994
Filed:
Sep. 29, 1989
B John Bergot, Redwood City, CA (US);
Vergine Chakerian, San Mateo, CA (US);
Charles R Connell, Redwood City, CA (US);
J Scott Eadie, Indianapolis, IN (US);
Steven Fung, Palo Alto, CA (US);
N Davis Hershey, San Carlos, CA (US);
Linda G Lee, Palo Alto, CA (US);
Steven M Menchen, Fremont, CA (US);
Sam L Woo, Redwood City, CA (US);
Applied Biosystems, Inc., Foster City, CA (US);
Abstract
A spectrally resolvable set of rhodamine dyes are provided for use in the chain termination method of nucleic acid sequencing. A different rhodamine dye from the group consisting of tetramethylrhodamine, rhodamine X, rhodamine 6G, and rhodamine 110 is attached to the base of each of the dideoxynucleotides used in the sequencing method by way of an alkynylamino linker. Preferably, the labeled dideoxynucleotides are incorporated into the growing DNA chains by Taq DNA polymerase.