Location History:
- Ness Ziona, IL (2010 - 2013)
- Nexx Ziona, IL (2014)
Company Filing History:
Years Active: 2010-2014
Title: Avigdor Shafferman: Innovator in Vaccine Development
Introduction
Avigdor Shafferman is a prominent inventor based in Ness Ziona, Israel, known for his significant contributions to the field of vaccine development. With a total of three patents, Shafferman is dedicated to advancing healthcare solutions, particularly for infectious diseases.
Latest Patents
Shafferman's latest patents showcase his innovative approach to combating malaria and tuberculosis. His first patent focuses on malaria vaccine compositions and constituents that elicit cell-mediated immunity. The invention offers a polyepitope construct that targets a broad spectrum of malaria parasites, covering the majority of HLA alleles. This includes epitopes from both highly variable and highly conserved regions of the circumsporozoite protein (CSP), which are crucial for immune response.
His second notable patent is for a recombinant Bacille Calmette-Guerin (BCG) tuberculosis vaccine. This vaccine is designed to elicit immune responses against Mycobacterium tuberculosis at all stages of infection and disease. The innovative subunit-based vaccine includes overexpressed Mtb antigens and incorporates the up-regulation of a portion of the DosR regulon. This development aims to provide protective effects against active Mtb infection both pre- and post-exposure, effectively preventing disease symptoms arising from latent Mtb infections.
Career Highlights
Avigdor Shafferman is currently working with the Aeras Global Tuberculosis Vaccine Foundation. His role within this organization highlights his commitment to addressing global health challenges through innovative vaccine solutions.
Collaborations
Throughout his career, Shafferman has collaborated with talented individuals such as Anat Zvi and John Fulkerson. These partnerships have allowed for the exchange of ideas and have fostered an environment of innovation aimed at improving vaccine efficacy and safety.
Conclusion
In conclusion, Avigdor Shafferman is a key figure in the realm of vaccine innovation, particularly in the fight against malaria and tuberculosis. His patents demonstrate his dedication to developing effective immunizations that enhance public health outcomes. As he continues to work with esteemed colleagues at Aeras Global Tuberculosis Vaccine Foundation, Shafferman is sure to make lasting contributions to the field of infectious disease prevention.