The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Jan. 12, 2009
Applicants:
Avigdor Shafferman, Nexx Ziona, IL;
Anat Zvi, Gedera, IL;
John Fulkerson, Silver Spring, MD (US);
Jerald C. Sadoff, Washington, DC (US);
Inventors:
Avigdor Shafferman, Nexx Ziona, IL;
Anat Zvi, Gedera, IL;
John Fulkerson, Silver Spring, MD (US);
Jerald C. Sadoff, Washington, DC (US);
Assignee:
Aeras Global TB Vaccine Foundation, Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); A61K 49/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Malaria vaccines based on polyepitope constructs that elicit cell-mediated immunity against a broad spectrum of malaria parasites and which cover the majority of HLA alleles are provided. Epitopes in the polyepitope constructs are from regions of thecircumsporozoite protein (CSP) known to contain CD4 and CD8 T cell epitopes, and include both epitopes from highly variable and highly conserved regions of CSP.