Company Filing History:
Years Active: 1997-2010
Title: Ashima Saxena: Innovator in Biochemical Research
Introduction
Ashima Saxena is a prominent inventor based in Fairfax Station, VA (US). She has made significant contributions to the field of biochemical research, particularly in the development of therapeutic methods and preparations. With a total of 5 patents, her work has garnered attention for its innovative approaches to addressing critical health challenges.
Latest Patents
One of her latest patents focuses on the large-scale production of human serum butyrylcholinesterase as a bioscavenger. This patent discloses methods for the large-scale preparation of human butyrylcholinesterase (HuBChE) from Cohn Fraction IV-4. The methods provide HuBChE preparations that are about 99% or more pure, with recovery yields of approximately 60%. Additionally, the patent discusses the pharmacokinetics, safety, toxicity, stability, and efficacy of these HuBChE preparations.
Another notable patent involves liposomes containing novel targeting and/or fusogenic peptides. This invention describes a novel targeting peptide from the C-terminal of endothelin and/or a fusogenic peptide from hemagglutinin, which are conjugated to the carboxy group of 1,2-dioleoyl-sn-glycero-3-succinate and incorporated into liposomes for therapeutic treatment. The targeting peptide directs liposomes to lung cells, making it useful for delivering liposomes encapsulating cholinesterase genes, particularly the HuBChE gene, as a treatment against nerve agents.
Career Highlights
Ashima Saxena works for the US Government as represented by the Secretary of the Army. Her role involves significant research and development efforts aimed at enhancing biochemical applications for military and civilian use. Her innovative work has positioned her as a key figure in her field.
Collaborations
Throughout her career, Ashima has collaborated with notable colleagues, including Bhupendra P Doctor and Donald M Maxwell. These collaborations have further enriched her research and contributed to the advancement of her projects.
Conclusion
Ashima Saxena's contributions to biochemical research through her patents and innovative methods highlight her role as a leading inventor in her field. Her work continues to pave the way for advancements in therapeutic applications and health solutions.