The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2010
Filed:
Apr. 10, 2007
Bhupendra P. Doctor, Potomac, MD (US);
Ashima Saxena, Fairfax, VA (US);
Wei Sun, Gaithersburg, MD (US);
Chunyuan Luo, North Potomac, MD (US);
Prasanthi Tipparaju, Rockville, MD (US);
Irwin Koplovitz, Bel Air, MD (US);
David E. Lenz, Belcamp, MD (US);
Michelle C. Ross, Edgewood, MD (US);
Bhupendra P. Doctor, Potomac, MD (US);
Ashima Saxena, Fairfax, VA (US);
Wei Sun, Gaithersburg, MD (US);
Chunyuan Luo, North Potomac, MD (US);
Prasanthi Tipparaju, Rockville, MD (US);
Irwin Koplovitz, Bel Air, MD (US);
David E. Lenz, Belcamp, MD (US);
Michelle C. Ross, Edgewood, MD (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Disclosed herein are methods for the large-scale preparation of human butyrylcholinesterase (HuBChE) preparations from Cohn Fraction IV-4. As disclosed, the methods provide HuBChE preparations that are about 99% or more pure with recovery yields of about 60%. Also disclosed are the pharmacokinetics, safety and toxicity, stability and efficacy of the HuBChE preparations.