Arne Holm

Title: Arne Holm: Innovator in Peptide Research

Introduction

Arne Holm is a distinguished inventor based in Holte, Denmark. He has made significant contributions to the field of peptide research, holding a total of five patents. His work focuses on developing innovative therapeutic methods and diagnostic tools, particularly in relation to cancer treatment and infectious diseases.

Latest Patents

One of Arne Holm's latest patents is titled "Peptide antagonists of the human urokinase receptor and method for selecting them." This invention presents a novel set of inhibitors that disrupt the binding interaction between human urokinase plasminogen activator (uPA) and its cell surface receptor (uPAR). The inhibitors consist of peptide fragments, which may include uncommon substituted amino acids and peptoid sequences. This invention also explores the therapeutic use of these peptides, especially for cancer treatment, by utilizing a modified non-human mammalian receptor that the inhibitors target.

Another significant patent is related to "Osp-C derived peptide fragments." This diagnostic method employs short C-terminal fragments of the OspC protein. The essential amino acids Pro-Lys-Pro are highlighted for their immune reactivity in patients suffering from early borreliosis. The patent also discusses the development of vaccines utilizing these short peptides and methods for their preparation.

Career Highlights

Arne Holm has worked with notable organizations such as Riso National Laboratory and Pence, Inc. His experience in these institutions has allowed him to advance his research and contribute to the scientific community significantly.

Collaborations

Throughout his career, Arne has collaborated with esteemed colleagues, including Rolf Henrik Berg and Kristoffer Almdal. These partnerships have fostered innovation and have been instrumental in the development of his patented technologies.

Conclusion

Arne Holm's contributions to peptide research and his innovative patents demonstrate his commitment to advancing medical science. His work not only enhances our understanding of peptide interactions but also paves the way for new therapeutic and diagnostic solutions.