The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 1998

Filed:

Jun. 15, 1994
Applicant:
Inventors:

Robert S Hodges, Edmonton, CA;

Randall T Irvin, Sherwood Park, CA;

Arne Holm, Holte, DK;

Wah Y Wong, Edmonton, CA;

Hasmukh B Sheth, Edmonton, CA;

Devon L Husband, Edmonton, CA;

Assignee:

Pence, Inc., Edmonton, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
435-71 ; 436501 ; 436518 ; 436531 ; 436543 ; 530333 ; 530334 ;
Abstract

A combinatorial library composition and method for using the library to construct oligomers effective to bind to a selected ligand is disclosed. The library composition includes at least two sets of ar oligomer libraries, each library set having selected oligomer subunit positions filled by known subunits, and other subunit positions containing permutations of subunits. In the selection method, oligomers from each library set are identified, and a new permutation library formed of subunits corresponding to the highest binding affinity oligomers in each library is screened for binding affinity to the selected ligand.


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