Armin Ruf

Title: Armin Ruf: Innovator in RNA Polymerase and Pharmaceutical Compounds

Introduction

Armin Ruf is a notable inventor based in Freiburg, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of RNA polymerase variants and pharmaceutical compounds. With a total of 3 patents, his work has had a considerable impact on both research and industry.

Latest Patents

One of Armin Ruf's latest patents focuses on T7 RNA polymerase variants with enhanced thermostability. This invention provides improved variants of T7 RNA polymerase by introducing novel mutations that lead to enhanced thermostability of the enzyme. The advantageous amino acid substitutions occur at positions Val426, Ser633, Val650, Thr654, Ala702, and Val795, as well as combinations thereof. Another significant patent involves sulfonamide derivatives, which are compounds that can be utilized in pharmaceutical compositions. These compounds are defined by a specific formula and include pharmaceutically acceptable salts and esters.

Career Highlights

Throughout his career, Armin Ruf has worked with prominent companies in the pharmaceutical industry. Notably, he has been associated with Hoffmann-La Roche Inc. and Roche Diagnostics Operations, Inc. His work in these organizations has allowed him to contribute to groundbreaking research and development in biotechnology.

Collaborations

Armin Ruf has collaborated with several esteemed colleagues, including Harald Sobek and Johann-Peter Thalhofer. These collaborations have further enriched his research and innovation efforts.

Conclusion

Armin Ruf's contributions to the fields of RNA polymerase and pharmaceutical compounds highlight his role as a significant inventor. His innovative patents and collaborations with leading companies and professionals underscore his impact on biotechnology.