Company Filing History:
Years Active: 2021-2023
Title: Aristides Tagalakis: Innovator in Nucleic Acid Delivery
Introduction
Aristides Tagalakis is a notable inventor based in London, GB. He has made significant contributions to the field of nucleic acid delivery, holding 2 patents that showcase his innovative approaches. His work focuses on developing non-viral delivery systems that enhance the efficiency of gene therapy.
Latest Patents
Tagalakis's latest patents include "Anionic nanocomplexes for nucleic acid delivery." This invention describes a non-viral delivery complex that features a cationic core, which is a nanoparticle comprising a peptide with a polycationic nucleic acid binding component, a cleavable spacer element, and a cell surface receptor binding component. The complex also includes a nucleic acid and optionally a cationic lipid, all surrounded by an anionic liposomal coating derived from a subject's cells. Additionally, he has patented "Lipids and complexes for the delivery of biologically-active material to cells." This patent details a lipid that comprises a tri-chain cation with a cationic head group and three or more hydrocarbyl groups, designed for use in non-viral gene delivery systems. The formulation demonstrates exceptional nucleic acid transfection when combined with targeting peptides.
Career Highlights
Throughout his career, Tagalakis has worked with various companies, including UCL Business Plc and Ryboquin Company Limited. His experience in these organizations has contributed to his expertise in the field of biotechnology and gene delivery systems.
Collaborations
Tagalakis has collaborated with notable professionals in his field, including Stephen Lewis Hart and Helen Claire Hailes. These collaborations have likely enriched his research and development efforts.
Conclusion
Aristides Tagalakis is a prominent inventor whose work in nucleic acid delivery systems has the potential to advance gene therapy significantly. His innovative patents and collaborations reflect his commitment to improving biotechnological solutions.