The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Mar. 10, 2017
Applicant:
Ryboquin Company Ltd, London, GB;
Inventors:
Helen Claire Hailes, London, GB;
Alethea Bernice Tabor, London, GB;
Mohn Firouz Mohd Mustapa, London, GB;
Stephen Lewis Hart, London, GB;
Aristides Tagalakis, London, GB;
Assignee:
RYBOQUIN COMPANY LTD, London, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/28 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07C 217/28 (2013.01); A61K 47/543 (2017.08); A61P 35/00 (2018.01);
Abstract
A lipid comprising a tri-chain cation having a cationic head group and three or more Chydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Exceptionally good nucleic acid transfection is observed when nucleic acid and targeting peptides are formulated with the lipid of the invention (or lipid formulated with a co-lipid) into a LPD complex.