The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Jan. 10, 2019
Applicant:
Ucl Business Plc, London, GB;
Inventors:
Stephen Hart, London, GB;
Aristides Tagalakis, London, GB;
Assignee:
UCL Business PLC, Greater London, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61P 35/00 (2006.01); A61K 31/7088 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 31/7088 (2013.01); A61K 38/1709 (2013.01); A61P 35/00 (2018.01);
Abstract
A non-viral delivery complex comprising a cationic core which is a nanoparticle comprising a peptide having a polycationic nucleic acid binding component, a cleavable spacer element and a cell surface receptor binding component; a nucleic acid and optionally a cationic lipid; and an anionic liposomal coating surrounding the cationic core, said coating comprising lipids from a subject's cells. Also related formulations, uses and methods.