Company Filing History:
Years Active: 2014-2020
Title: Anup Singh: Innovator in Magnetic Resonance Imaging
Introduction
Anup Singh is a prominent inventor based in Philadelphia, PA (US). He has made significant contributions to the field of magnetic resonance imaging (MRI), holding a total of 3 patents. His work focuses on innovative techniques that enhance the capabilities of MRI in medical diagnostics.
Latest Patents
Anup Singh's latest patents include groundbreaking methods for non-invasive imaging. One of his notable inventions is related to the magnetic resonance imaging of poly-L-glutamate. This non-invasive imaging approach utilizes chemical exchange saturation transfer (CEST) and magnetic resonance spectroscopy (MRS) to monitor the cleavage of the poly-L-glutamate (PLG) backbone. The technique allows for the detection of exchangeable -NH2 protons in PLG, providing valuable information on malignant tissue and tumor aggressiveness, as well as monitoring treatment efficacy.
Another significant patent involves the use of endogenous magnetization contrast in MRI. This method models a conventional magnetization transfer (CMT) spectrum using z-spectral data to generate magnetization transfer ratio maps. By removing contributions from the CMT spectrum, the technique reveals new contrast due to chemical exchange saturation transfer (CEST) and magnetization transfer/exchange effects from aliphatic protons associated with labile proteins, peptides, and lipids. This innovation enhances the visibility of biological tissues, improves segmentation in brain images, and provides better visualization of proteins and lipids.
Career Highlights
Anup Singh is affiliated with the University of Pennsylvania, where he continues to advance research in MRI technology. His work has garnered attention for its potential to improve diagnostic imaging and patient outcomes.
Collaborations
Anup has collaborated with esteemed colleagues such as Ravinder Reddy and Hari Hariharan, contributing to a dynamic research environment that fosters innovation.
Conclusion
Anup Singh's contributions to magnetic resonance imaging exemplify the impact of innovative thinking in medical technology. His patents reflect a commitment to enhancing diagnostic capabilities and improving patient care through advanced imaging techniques.