Annamaria Mocciaro

Title: Annamaria Mocciaro: Innovator in Genome Editing and Immunotherapy

Introduction

Annamaria Mocciaro is a prominent inventor based in San Francisco, CA, known for her groundbreaking work in the fields of genome editing and immunotherapy. With a total of four patents to her name, she has made significant contributions to the development of innovative methods for enhancing T cell functionality in cancer treatment.

Latest Patents

Mocciaro's latest patents include "Methods for selection and generation of genome edited T cells." This patent describes methods for isolating clonal populations of T cells with defined genetic modifications, utilizing a microfluidic device with sequestration pens. The process involves maintaining individual T cells that have undergone genomic editing, expanding them into clonal populations, and detecting specific genetic markers indicative of successful edits. Another notable patent is "Tumor infiltrating cells engineered to express a pro-inflammatory polypeptide." This invention provides methods for preparing tumor infiltrating cells that express a pro-inflammatory polypeptide, aimed at countering the immunosuppressive environment surrounding tumors. By delivering the polypeptide directly from the tumor infiltrating cells, the method minimizes side effects associated with systemic administration.

Career Highlights

Annamaria has worked with notable organizations such as Berkeley Lights, Inc. and the University of California. Her experience in these institutions has allowed her to collaborate on cutting-edge research and development projects that push the boundaries of current medical technologies.

Collaborations

Mocciaro has collaborated with esteemed colleagues, including Gregory G Lavieu and Xiao Guan Radstrom. These partnerships have contributed to her innovative approaches in the field of immunotherapy and genome editing.

Conclusion

Annamaria Mocciaro's contributions to the fields of genome editing and immunotherapy highlight her role as a leading inventor. Her innovative patents and collaborations reflect her commitment to advancing medical science and improving patient outcomes.