Company Filing History:
Years Active: 2011-2015
Title: **Innovator Spotlight: Angela Hofhine**
Introduction
Angela Hofhine, an accomplished inventor based in Durham, North Carolina, has made significant contributions to the field of insecticide development. With a total of two patents to her name, her work focuses on innovative methods and compositions that enhance the identification and effectiveness of insect repellent compounds.
Latest Patents
Hofhine's latest patents showcase her expertise in the realm of entomology and biochemistry. One notable invention is "Screening Assay for Insecticides," which revolves around polypeptides, specifically DmShaI, as crucial targets for insecticides. This invention seeks to improve the efficiency of insect pest control by providing a targetable approach for developing effective insecticides.
Her other significant patent, "Methods and Compositions for the Identification of Insect Repellent Compounds," presents innovative methods for pinpointing candidate compounds that can modulate cation transport through a transient receptor potential (TRP) channel within cells. This patent outlines a systematic methodology involving the use of recombinant nucleic acid sequences to express TRP channel gene products, followed by evaluating the effects of candidate compounds on cation transport. The invention includes a detailed description of nucleic acid and amino acid sequences pertaining to insect TRP channel gene products, along with antibodies that bind to these channels.
Career Highlights
Angela Hofhine has cultivated her career through significant roles at prestigious organizations. She has worked at Duke University, one of the top research institutions in the United States, where her research has helped advance the scientific understanding of insect behavior and pest control methods. Additionally, she has contributed her expertise to BASF SE Corporation, a global chemical company known for its innovations in agriculture and pest management solutions.
Collaborations
Throughout her career, Hofhine has collaborated with noted professionals in her field, including William D Tracey, Jr. and Nancy Stearns. These partnerships have further propelled her research, enabling her to combine diverse expertise and enrich her contributions to the scientific community.
Conclusion
Angela Hofhine’s work exemplifies the intersection of innovation and practicality in developing solutions for real-world problems. Her two patents reflect her dedication to advancing insect repellent technologies and provide valuable insights into the potential for targeted pest control strategies. As she continues her research, Hofhine remains a key figure in her field, paving the way for future innovations in insect management.