This inventor holds 3 USPTO granted patents. Top assignees: Medical Research Council, University of Utah Research Foundation. Active years: 2005-2009.
Company Filing History:


Years Active: 2005-2009
Title: The Innovations of Andrew Philip Carter
Introduction
Andrew Philip Carter is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of molecular biology, particularly in the study of ribosomes. With a total of 3 patents, his work has implications for antibiotic development and understanding ribosomal structures.
Latest Patents
Carter's latest patents include groundbreaking research on the crystal structure of the 30S ribosome. This invention provides an X-ray crystal structure of the 30S ribosome, obtained from the 30S subunit, which has a tetragonal space group P422. The unit cell dimensions are a=401.4±4.0 Å, b=401.4±4.0 Å, and c=175.9±5.0 Å. An advantageous feature of this structure is its ability to diffract beyond 3 Å resolution. The data may be utilized for the rational design and modeling of inhibitors for the 30S ribosome, which have potential use as antibiotics.
Another significant patent by Carter is related to the crystal structure of antibiotics bound to the 30S ribosome. This invention provides high-resolution X-ray crystal structures of the 30S ribosome, also obtained from the 30S subunit, with the same tetragonal space group P422. The structure is bound to antibiotics such as paromomycin, streptomycin, spectinomycin, tetracycline, pactamycin, and hygromycin B. This invention also diffracts at about 3 Å resolution and provides three-dimensional atomic coordinates of the 30S ribosome, which can be used for the rational design and modeling of inhibitors.
Career Highlights
Carter has worked with esteemed organizations such as the Medical Research Council and the University of Utah Research Foundation. His research has significantly advanced the understanding of ribosomal structures and their interactions with antibiotics.
Collaborations
Carter has collaborated with notable scientists, including Venkatraman Ramakrishnan and Ditlev Egeskov Brodersen. These collaborations have further enriched his research and contributions to the field.
Conclusion
Andrew Philip Carter's innovative work in the field of molecular biology has led to important advancements in understanding ribosomal structures and their potential applications in antibiotic development. His contributions continue to influence research in this critical area.