Oceanside, CA, United States of America

Andrew Mamoru Kawasaki

USPTO Granted Patents = 31 


 

Average Co-Inventor Count = 3.2

ph-index = 17

Forward Citations = 1,658(Granted Patents)


Location History:

  • Carlsbad, CA (US) (2000 - 2003)
  • Oceanside, CA (US) (1996 - 2006)
  • San Diego, CA (US) (2006 - 2022)

Company Filing History:


Years Active: 1996-2022

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31 patents (USPTO):

Title: Andrew Mamoru Kawasaki: Innovator and Inventor

Introduction

Andrew Mamoru Kawasaki, based in Oceanside, CA, is a distinguished inventor known for his significant contributions to the field of medicinal chemistry. With a remarkable portfolio of 31 patents, Kawasaki has developed innovative solutions aimed at improving pharmacological treatment options.

Latest Patents

Kawasaki's latest patents showcase his expertise and innovative thinking. One notable invention is the development of analogs of dextromethorphan, which exhibit balanced receptor activities. These substituted analogs demonstrate substantial binding affinity at both NMDA and sigma-1 receptors, while also being degraded by human liver enzymes at a slower rate compared to dextromethorphan. This advancement offers alternatives that can provide similar benefits without the need for a cytochrome P-450 enzyme inhibitor.

Another significant patent involves the synthesis and characterization of an Isometheptene isomer, particularly the (R)-enantiomer. This compound is praised for its selective activity as a centrally acting ligand for Imidazoline subtype 1 (I1) receptor sites. The invention promises an antihypertensive composition beneficial in treating migraine and neurogenic pain associated with abdominal distress, boasting lower side effects compared to its racemate form.

Career Highlights

Kawasaki has made a substantial impact in the pharmaceutical industry, having collaborated with leading companies such as Isis Pharmaceuticals and Arena Pharmaceuticals. His work has paved the way for advancements in drug development, particularly in the realm of pain management and hypertension.

Collaborations

In his professional journey, Andrew has collaborated with notable colleagues, including Phillip Dan Cook and Muthiah Manoharan. Their collective efforts have undoubtedly enriched the development of innovative therapeutics.

Conclusion

Andrew Mamoru Kawasaki stands as a prominent figure in the field of innovation, particularly in medicinal chemistry. His contributions through various patents highlight the ongoing potential for advancements in healthcare, offering hope and improved treatment options for patients in need.

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