Baltimore, MD, United States of America

Andrew Fire

USPTO Granted Patents = 16 

 

Average Co-Inventor Count = 4.8

ph-index = 7

Forward Citations = 1,892(Granted Patents)


Location History:

  • Baltimore, MD (US) (1997 - 2015)
  • Stanford, CA (US) (2015 - 2017)
  • Washington, DC (US) (2012 - 2019)

Company Filing History:


Years Active: 1997-2024

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16 patents (USPTO):Explore Patents

Title: Andrew Fire: A Pioneer in Genetic Research

Introduction

Andrew Fire is a renowned inventor and researcher based in Baltimore, MD. He has made significant contributions to the field of genetics, holding a total of 16 patents. His work has advanced our understanding of gene expression and genomic variations, paving the way for innovative approaches in genetic research.

Latest Patents

Among his latest patents, one focuses on the detection and analysis of structural variations in genomes. This invention provides compositions and methods for detecting dynamic loci in a genome, which may include structural variations resulting from DNA recombination, duplications, insertions, deletions, transpositions, and epigenetic changes. The methods utilize microfluidic platforms and functionalized polymer matrices to determine mechanisms of cell-type-specific, programmed genomic heterogeneity. Another notable patent involves genetic inhibition by double-stranded RNA. This process introduces RNA into living cells to inhibit the expression of target genes. The inhibition is sequence-specific, as the nucleotide sequences of the RNA's duplex region and the target gene are identical. This invention distinguishes itself from prior methods of gene expression interference.

Career Highlights

Andrew Fire has had a distinguished career, working at prestigious institutions such as the Carnegie Institution of Washington and the University of Massachusetts. His research has garnered attention and respect within the scientific community, contributing to advancements in genetic engineering and molecular biology.

Collaborations

Throughout his career, Andrew has collaborated with notable scientists, including Hiroaki Tabara and Craig C. Mello. These collaborations have further enriched his research and expanded the impact of his inventions.

Conclusion

Andrew Fire's innovative work in genetics has led to significant advancements in our understanding of gene expression and structural variations in genomes. His contributions continue to influence the field and inspire future research.

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