The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Oct. 08, 2012
Carnegie Institution of Washington, Washington, DC (US);
The University of Massachusetts, Boston, MA (US);
Andrew Fire, Baltimore, MD (US);
Stephen Kostas, Towson, MD (US);
Mary Montgomery, St. Paul, MN (US);
Lisa Timmons, Lawrence, KS (US);
SiQun Xu, Ballwin, MO (US);
Hiroaki Tabara, Mishima, JP;
Samuel E. Driver, Providence, RI (US);
Craig C. Mello, Shrewsbury, MA (US);
The Carnegie Institution of Washington, Washington, DC (US);
The University of Massachusetts, Boston, MA (US);
Abstract
A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duplex region of the RNA and of a portion of the target gene are identical. The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods.