Andrew A Burns

Title: Innovations of Andrew A Burns in Nanotechnology

Introduction

Andrew A Burns is a prominent inventor based in Schenectady, NY (US), known for his significant contributions to the field of nanotechnology. With a total of 13 patents to his name, he has made remarkable advancements, particularly in the development of silica-based nanoparticles for medical applications.

Latest Patents

One of his latest patents focuses on multimodal silica-based nanoparticles. This invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring, and treatment of diseases such as cancer. The nanoparticle features a range of diameters, including between about 0.1 nm and about 100 nm, and is designed to have greater brightness and fluorescent quantum yield than free fluorescent compounds. Additionally, it exhibits high biostability and biocompatibility. To enhance urinary excretion, the nanoparticle may be coated with an organic polymer like poly(ethylene glycol) (PEG). The small size and silica base minimize toxicity when administered in vivo. Furthermore, the nanoparticle can be conjugated to a ligand for targeting specific cell types, such as tumor markers, and may also carry therapeutic agents. It is designed to be detectable by various imaging techniques, including positron emission tomography (PET) and magnetic resonance imaging (MRI), by incorporating radionuclides or paramagnetic ions.

Career Highlights

Throughout his career, Andrew A Burns has