Zurich, Switzerland

Andrea Vasella


 

Average Co-Inventor Count = 3.6

ph-index = 2

Forward Citations = 104(Granted Patents)


Location History:

  • Z urich, CH (1997 - 2000)
  • Zürich, CH (2013 - 2016)
  • Zurich, CH (2022)

Company Filing History:


Years Active: 1997-2022

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8 patents (USPTO):Explore Patents

Title: Andrea Vasella: Innovator in Antibacterial Drug Development

Introduction

Andrea Vasella is a prominent inventor based in Zurich, Switzerland. She has made significant contributions to the field of antibacterial drug development, particularly through her innovative work on aminoglycoside antibiotics. With a total of 8 patents to her name, Vasella's research focuses on enhancing the efficacy of existing antibacterial agents.

Latest Patents

Vasella's latest patents include advancements in apramycin derivatives. This invention relates to derivatives of apramycin-based aminoglycoside antibacterial drugs modified in positions C5 and/or C6 and O5 and/or O6. The modifications impart favorable properties regarding increased selectivity and retention of activity in the presence of resistance determinants of the AAC(3) class. Furthermore, the invention relates to these compounds for use in the therapy of bacterial infections by systemic administration, especially in cases where the infection is caused by a pathogen comprising a resistance determinant of the AAC(3) class, particularly AAC(3)-IV. Another notable patent involves neomycin and paromomycin derivatives. This disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6', C2′, and/or C5″. The modifications provide favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits, and increased selectivity, enabling systemic use of the compounds.

Career Highlights

Throughout her career, Andrea Vasella has worked with esteemed institutions such as Wayne State University and Universität Zürich. Her research has significantly impacted the field of antibacterial therapies, making her a key figure in the ongoing battle against antibiotic resistance.

Collaborations

Vasella has collaborated with notable colleagues, including Sven N. Hobbie and Erik Boettger. These partnerships have further enriched her research and contributed to her innovative developments in the field.

Conclusion

Andrea Vasella's work exemplifies the importance of innovation in the fight against bacterial infections. Her contributions to the development of aminoglycoside antibiotics are paving the way for more effective treatments in the future.

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