Andrea Mattarei

Title: Andrea Mattarei: Innovator in Opioid Modulation

Introduction

Andrea Mattarei is a notable inventor based in Perarolo di Vigonza, Italy. She has made significant contributions to the field of pharmacology, particularly in the development of structurally modified opioids. With a total of 3 patents, her work focuses on improving drug efficacy and safety.

Latest Patents

Mattarei's latest patents include innovative approaches to opioid modulation. One patent addresses "Structurally modified opioids for prevention and treatment of diseases and conditions." This invention aims to enhance the modulating activity at the NMDAR, offering improved pharmacokinetic (PK) and pharmacodynamic (PD) parameters compared to existing drugs. The structural modifications can be achieved through various synthetic processes, including de novo synthesis and modifications at intermediate steps.

Another significant patent involves "Compositions and methods of use comprising substances with neural plasticity actions administered at non-psychedelic/psychotomimetic dosages and formulations." This invention utilizes serotonin (5-HT) receptor agonists and NMDAR modulating substances to treat various diseases and enhance neural functions.

Career Highlights

Throughout her career, Andrea Mattarei has worked with several companies, including Arbormentis LLC and Mggm LLC. Her expertise in opioid modulation has positioned her as a key player in the pharmaceutical industry.

Collaborations

One of her notable collaborators is Charles E. Inturrisi, who has contributed to her research endeavors.

Conclusion

Andrea Mattarei's innovative work in opioid modulation and neural plasticity represents a significant advancement in pharmacological research. Her patents reflect a commitment to improving treatment options for various conditions, showcasing her impact on the field.