Location History:
- Bethany, OK (US) (1990)
- Carmel, IN (US) (1995 - 2010)
Company Filing History:
6 out of 1,648 
3 out of 480 
1 out of 1,164 
Years Active: 1990-2010
Title: Inventor Spotlight: Allan R. Dorn
Introduction
Allan R. Dorn, based in Carmel, Indiana, is an accomplished inventor with an impressive portfolio of 12 patents to his name. His innovative contributions, particularly in the field of drug assays and enzyme modifications, exemplify the intersection of scientific research and practical application.
Latest Patents
Dorn's latest patents include groundbreaking work on single receptor assays for immunosuppressive drugs. This method presents a highly specific homogeneous assay that employs an immunophilin in a single receptor format. In this competitive immunoassay, the assay utilizes a single receptor, wherein an immunophilin replaces traditional antibodies. The method showcases a competition between a drug conjugate and the drug analyte for a limited number of binding sites available on the immunophilin. Furthermore, he has developed a microparticle agglutination assay format employing the immunophilin, which can either be bound to a particle or remain in solution.
Additionally, a notable invention from Dorn pertains to the production of recombinant histidine-tagged inosine monophosphate dehydrogenase (IMPDH) polypeptides. The invention details a modified IMPDH polypeptide, featuring a histidine tag and enhancements to its subdomain for increased stability compared to the wild-type IMPDH. This invention also encompasses methods, nucleic acid molecules, vectors, and host cells for the fabrication of these modified polypeptides, along with associated kits.
Career Highlights
Throughout his career, Allan R. Dorn has gained valuable experience working with prominent companies such as Roche Diagnostics Operations, Inc. and Roche Diagnostics GmbH. His work at these organizations emphasizes his role in driving forward medical and diagnostic innovations that contribute to healthcare advancements.
Collaborations
In his journey, Dorn has collaborated with esteemed colleagues, including Mitali Ghoshal and Gerald F. Sigler. These partnerships have undoubtedly enriched his contributions to the field and fostered a collaborative spirit that is crucial for innovation.
Conclusion
Allan R. Dorn stands out as a leading inventor whose patents reflect significant advancements in the development of drug assays and enzyme production. His innovative spirit and dedication to research continue to make a lasting impact on the field, paving the way for future breakthroughs in medical diagnostics and treatment.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.