The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2010
Filed:
Aug. 31, 2006
Gerald Sigler, Carmel, IN (US);
Mitali Ghoshal, Fishers, IN (US);
Allan Dorn, Carmel, IN (US);
Shaker Rashid, Fishers, IN (US);
Gerald Sigler, Carmel, IN (US);
Mitali Ghoshal, Fishers, IN (US);
Allan Dorn, Carmel, IN (US);
Shaker Rashid, Fishers, IN (US);
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
A highly specific homogeneous assay method for an immunosuppressive drug using an immunophilin in a single receptor format is provided. In the simplest format, a single receptor is utilized analogous to a competitive immunoassay whereby an immunophilin is substituted for an antibody, and a competition results between a drug conjugate and the drug analyte for a limited number of immunophilin binding sites. In a microparticle agglutination assay format, an immunophilin is either bound to a particle or in solution. In the case where an immunophilin is bound to a particle, a polyvalent conjugate of the drug analyte is present in solution.