Trappe, PA, United States of America

Alison Francis Chalker


Average Co-Inventor Count = 9.0

ph-index = 2

Forward Citations = 20(Granted Patents)


Company Filing History:


Years Active: 2000-2002

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18 patents (USPTO):Explore Patents

Title: Celebrating the Innovations of Alison Francis Chalker

Introduction: Alison Francis Chalker, based in Trappe, PA, is a remarkable inventor with an impressive portfolio of 18 patents. Her contributions to the field of biotechnology focus on the development of antibacterial compounds through innovative polypeptides and polynucleotides.

Latest Patents: Among her recent inventions, the inFB patent stands out. This invention provides infB polypeptides and the corresponding polynucleotides that encode these polypeptides. Notably, her methods for producing such polypeptides by recombinant techniques offer exciting possibilities for advancements in antibacterial screening. Another significant patent is for trmD, which presents trmA methyl transferase (trmD) polypeptides and the polynucleotides involved in their production from Streptococcus pneumoniae. This invention also encompasses methods to utilize these polypeptides for the screening of antibacterial compounds, showcasing her innovative approach in the realm of microbial research.

Career Highlights: Alison Chalker has made her mark at SmithKline Beecham Corporation, where she has utilized her expertise to further research and development in biotechnological applications. Her work has not only garnered patents but has also contributed to significant advancements in understanding bacterial resistance and potential treatments.

Collaborations: Throughout her career, Chalker has collaborated with notable colleagues, including Karen Anne Ingraham and David John Holmes. These collaborations have undoubtedly enriched her research, fostering a dynamic environment for innovative discoveries.

Conclusion: Alison Francis Chalker is not just an inventor; she is a pioneer in the field of biotechnology. With her extensive patent portfolio and collaborative spirit, she continues to make strides toward combating bacterial infections. Her work is a testament to the impact of innovative thinking in healthcare solutions.

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