Location History:
- Kiryat Tivon, IL (2016)
- Kiryat Tivion, IL (2017 - 2018)
Company Filing History:
3 out of 964 
2 out of 811 
Years Active: 2016-2018
Title: Innovations by Alex Martin Szpilman
Introduction
Alex Martin Szpilman is an accomplished inventor based in Kiryat Tivion, Israel. He has made significant contributions to the field of pharmaceuticals, particularly in the development of Amphotericin B derivatives. With a total of 3 patents to his name, Szpilman's work focuses on enhancing the efficacy and safety of antifungal treatments.
Latest Patents
Szpilman's latest patents revolve around the creation of Amphotericin B derivatives. These embodiments provide derivatives of Amphotericin B that exhibit increased solubility and reduced toxicity compared to the original compound, while still retaining antifungal activity against various clinical fungal isolates. The derivatives include a polymer group with an amine group, which is linked to mycosamine through a stable linker, such as an amide linker. The general formula for these derivatives includes various configurations of R groups, which can be hydrogen, Calkyl, or phenyl, among others. This innovative approach aims to improve the therapeutic profile of Amphotericin B, making it a more viable option for treating fungal infections.
Career Highlights
Throughout his career, Szpilman has been associated with notable institutions such as the Technion Research & Development Foundation Ltd and Tel Aviv University. His work in these organizations has allowed him to advance his research and contribute to the scientific community significantly.
Collaborations
Szpilman has collaborated with esteemed colleagues, including Itai Benhar and Nir Osherov. These partnerships have fostered a collaborative environment that enhances the innovation process and leads to groundbreaking discoveries in the field of pharmaceuticals.
Conclusion
Alex Martin Szpilman is a prominent inventor whose work on Amphotericin B derivatives showcases his commitment to improving antifungal treatments. His contributions to the field are invaluable and continue to influence pharmaceutical research and development.