The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Aug. 06, 2014
Applicant:

Technion Research and Development Foundation Ltd., Haifa, IL;

Inventors:

Alex M. Szpilman, Kiryat Tivon, IL;

Michal Amar, Haifa, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/14 (2006.01); B01J 31/02 (2006.01); C07C 45/39 (2006.01);
U.S. Cl.
CPC ...
C07D 221/14 (2013.01); B01J 31/0244 (2013.01); C07C 45/39 (2013.01);
Abstract

Novel alpha-hydrogen substituted nitroxyl compounds and their corresponding oxidized (oxoammonium cations) and reduced (hydroxylamine) forms, and the use of such compounds, inter alia, for oxidation of primary and secondary alcohols to aldehydes and ketones, respectively; resolution of racemic alcohols; desymmetrization of meso-alcohol; as radicals and spin trapping reagents; and as polymerization agents. Processes for preparing the novel nitroxyl/oxoammonium/hydroxylamine compounds from the corresponding amines, and certain novel amine derivatives and their uses. The compounds and amine precursors are useful as ligands for transition metals and as organocatalysts in e.g., aldol reactions.


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