This inventor holds 7 USPTO granted patents and 9 published patent applications. Top assignee: Yale University. Active years: 2007-2024.
Location History:
- Wilton, CT (US) (2007 - 2021)
- New Haven, CT (US) (2018 - 2024)
Company Filing History:
Years Active: 2007-2024
Title: Alanna Schepartz Shrader: Innovator in Peptidic Materials and Designer Ribosomes
Introduction
Alanna Schepartz Shrader is a prominent inventor based in Wilton, CT (US). She has made significant contributions to the field of biochemistry, particularly in the development of innovative peptidic materials and designer ribosomes. With a total of seven patents to her name, her work has the potential to advance various applications in molecular biology and medicine.
Latest Patents
One of her latest patents focuses on "Peptidic materials that traffic efficiently to the cell cytosol and nucleus." This invention relates to modified peptidic oligomers that possess an enhanced ability to reach the cytosol or nucleus. In certain embodiments, these modified peptidic oligomer molecules are capable of delivering associated cargo molecules to the cytosol or nucleus. Additionally, other embodiments involve modified peptidic oligomer fusion molecules that can effectively reach these cellular compartments.
Another significant patent is titled "Designer ribosomes and methods of use thereof for incorporating non-standard amino acids into polypeptides." This invention provides engineered 23S rRNAs and methods for translating proteins that incorporate non-standard amino acids. Typically, the 23S rRNA includes mutations at specific positions, allowing a ribosome composed of this rRNA to catalyze the transfer of a non-standard amino acid onto a nascent peptide chain. The compositions and methods developed can be utilized to create polypeptides and sequence-defined polymers.
Career Highlights
Alanna Schepartz Shrader is affiliated with Yale University, where she continues her research and innovation in the field of biochemistry. Her work has garnered attention for its potential applications in various scientific and medical fields.
Collaborations
Throughout her career, Alanna has collaborated with notable colleagues, including Jason W K Chin and Reena Zutshi. These collaborations have further enriched her research and contributed to the advancement of her innovative projects.
Conclusion
Alanna Schepartz Shrader is a trailblazer in the realm of biochemistry, with her patents paving the way for new advancements in molecular biology. Her contributions to the development of peptidic materials and designer ribosomes highlight her role as a leading inventor in her field.