The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2011
Filed:
Apr. 21, 2005
Alanna Schepartz Shrader, Wilton, CT (US);
Scott A. Hart, San Diego, CA (US);
Joshua A. Kritzer, New Haven, CT (US);
Olen M. Stephens, New Haven, CT (US);
Alanna Schepartz Shrader, Wilton, CT (US);
Scott A. Hart, San Diego, CA (US);
Joshua A. Kritzer, New Haven, CT (US);
Olen M. Stephens, New Haven, CT (US);
Yale University, New Haven, CT (US);
Abstract
β-peptide regions of polypeptides can serve as structural mimics of α-helices in wild type proteins. Because α-helices of one protein often bind to a target protein in a biological pathway, a polypeptide that contains a helical β-peptide region can be used to disrupt this type of protein-protein binding. As a result, polypeptides that contain a helical β-peptide region can be used to treat conditions involving this type of protein-protein binding, such as viral infections and cell proliferation.