Lancaster, OH, United States of America

Alan Wayne Shafer



Average Co-Inventor Count = 4.0

ph-index = 4

Forward Citations = 57(Granted Patents)


Location History:

  • Albany, OH (US) (1997 - 2003)
  • Lancaster, OH (US) (1999 - 2005)

Company Filing History:


Years Active: 1997-2005

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12 patents (USPTO):Explore Patents

Title: Alan Wayne Shafer: Innovator in Leptin Research

Introduction

Alan Wayne Shafer is a notable inventor based in Lancaster, Ohio, with a significant contribution to the field of biological research. He holds a total of 12 patents, showcasing his innovative approaches to understanding and utilizing leptin, a hormone involved in regulating energy balance and body weight.

Latest Patents

Shafer's latest patents include groundbreaking methods for identifying compounds capable of supplementing the biological activity of leptin. This invention focuses on a variant form of the receptor for the obese gene product. It details methods for detecting this receptor variant in cells and tissues of obese individuals. Furthermore, it discusses techniques for inhibiting or down-regulating the expression of this variant in cells to enhance their responsiveness to weight regulation by leptin. Additionally, the invention explores methods for using compounds to directly activate signal transduction pathways associated with this ligand-receptor system. Another significant patent involves methods for using the obese product to stimulate hematopoietic development. This invention relates to various forms of a novel receptor expressed by hematopoietic and endothelial cells. It highlights the potential of leptin to stimulate the growth and development of receptor-positive hematopoietic and endothelial cells both in vitro and in vivo.

Career Highlights

Throughout his career, Shafer has worked with prominent companies such as Progenitor, Inc. and Indevus Pharmaceuticals, Inc. His work has significantly advanced the understanding of leptin and its applications in medical science.

Collaborations

Shafer has collaborated with notable individuals in his field, including H Ralph Snodgrass and Joseph Cioffi. These collaborations have contributed to the development of innovative solutions in biological research.

Conclusion

Alan Wayne Shafer's contributions to the field of leptin research through his patents and collaborations highlight his role as a significant innovator. His work continues to influence the understanding of obesity and its treatment.

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